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Product Information:

Suzetrigine phenol

Suzetrigine phenol is the phenolate form of the sodium channel modulator VX-548 (EX-A7354). Suzetrigine (VX-548) is an orally active and highly selective inhibitor of NaV1.8.

Cat. No.: EX-A9086    Purity: >98%
Chemical
Chemical structure of Suzetrigine phenol


For research only, Do not use for Human!

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SynonymsVX-548 phenol
CAS No.2649467-91-2
Purity>98%
FormulaC20H18F5N3O4
Mol Weight459.3666
Appearancesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Scarnati MS, et al. Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol. 2019 Feb;74:83-93.

[2]. Preparation of substituted tetrahydrofuran amides as modulators of sodium channels. World Intellectual Property Organization, WO2021113627 A1 2021-06-10.

CoACoA of Suzetrigine phenol

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